Blood Coagulation Protocol

   

“The leading cause of death in the western world is the formation of abnormal clots inside a blood vessel. It is important for healthy people to take steps to prevent this.” Life Extension

   

"In all my years of research as a professor of cardiovascular and pulmonary medicine, natto and nattokinase represents the most exciting new development in the prevention and treatment of cardiovascular related diseases. What makes nattokinase a particularly potent treatment is that it enhances the body's natural ability to fight blood clots in several different ways. Because it so closely resembles plasmin, it dissolves fibrin directly. In addition, it also enhances the body's production of both plasmin and other clot-dissolving agents, including endogenous urokinase. We have finally found a potent natural agent that can thin and dissolve clots effectively, with relative safety and without side effects."  Doctor Martin Milner

"In any complex fluid - whether it's blood, ketchup, or paint - the thinner it is, the less work it takes to pump it. Therefore, the thinner your blood, the easier it is for your heart to pump it around your body, the less the arteries will have to stretch, and the less injury the arteries will sustain."  Doctor Kenneth R. Kensey, MD, The Blood Thinner Cure

“Once we accept the need for long-term anti-platelet, anti-coagulant and anti-inflammatory therapy to deal with the newly recognized molecular risk factors such as fibrinogen, ultra sensitive C-reactive protein, Intracellular Adhesion Molecule (ICAM) etc., then I believe we will all start better serving the needs of our patients.”     Doctor Garry Gordon MD

“Fibrinogen promotes the negative activity of platelets by encouraging platelet aggregation.” Koenig

“Ginkgo biloba improves circulation and reduces platelet aggregation, as well as fibrinogen levels. Ginkgo counters blood viscosity and is routinely prescribed by clinicians for patients 50 years or older.” Life Extension

“Skipping breakfast nearly triples your blood clotting potential, leaving you more vulnerable to heart attacks and stroke. Blood platelet stickiness is lowest overnight then climbs rapidly when you wake up. Eating seems to somehow unstuck the platelets.”  Renata Cifkova Memorial University of Newfoundland

“It has recently been revealed that thrombotic clogging of the cerebral blood vessels may be a cause of dementia. It has been estimated that sixty percent of senile dementia patients in Japan is caused by thrombus. Natto can dissolve these thrombi.” Doctor of Medicine Hiroyuki Sumi, Japan Bio Science Laboratory Co. Ltd

“Researchers from Biotechnology Research Laboratories and JCR Pharmaceuticals Co. of Kobe, Japan, tested Nattokinase’s ability to dissolve a thrombus in the carotid arteries of rats. Animals treated with nattokinase regained 62 percent of blood flow, whereas those treated with plasmin regained just 15.8 percent of blood flow.^”  Prevent Heart Attack and Stroke with Potent Enzyme that Dissolves Deadly Blood Clots in Hours. Health Sciences Institute, March 2002

“Abnormal platelet stickiness increases atherosclerosis and further narrows the internal diameter of the artery, factors that predispose one to stroke and heart attack.” Braly 1985

“Ginger inhibits abnormal platelet aggregation by two methods; it acts as a potent inhibitor of thrombi and has twice the anti-platelet power as aspirin.” Life Extension

“While there are over 3000 enzymes in the body and there are more than 20 enzymes involved in the coagulation cascade that creates blood clots, there is only one enzyme that Mother Nature has provided to the human body that can dissolve the fibrin and break up blood clots. This enzyme is called plasmin. Unfortunately, the body's production of this decline with age. In addition to its decreased production with age, fibrinogen levels also rises 25mg/dl per decade in healthy people. In other words, as we age, our plasmin level reduces while our fibrinogen level rises. The resulting risk of cardiac accidents goes up.” Doctor Michael Lam MD

"Courmadin is one of the most dangerous drugs prescribed." Doctor Gary Gordon MD

"I believe that today combating this clot forming tendency has become essential for long-term survival for the majority of patients. I consider aspirin to be totally inadequate and the benefit-risk ratio causes me to not bother using it." Doctor Gary Gordon MD

"It is critical for a healthy body that we keep the colon clean and free of debris. The stress on the body is incalculable when toxins are reabsorbed into the overburdened bloodstream and taken to the already over worked liver." Doctor Anthony Cichoke

"Blood clots kill more than 600,000 Americans every year yet conventional medicine has largely ignored well-documented methods of reducing abnormal blood clot formation." Circulation Ahajournal

"Plasminogen synthesis and synthesis of its activators is reduced with age according to Doctor T. Astrup. This results in deposits of fibrin forming in the blood vessels." Doctor Anthony Cichoke

"Doctors Max Wolf and Karl Ransberger treated thousands of the elderly therapeutically with proteolytic enzyme mixtures and vitamin E. Benefits included normalization of cholesterol levels and other serum lipid levels; plus an increase in blood clot lysing activity." Doctor Anthony Cichoke

"Enzymes' role in maintaining blood fluidity and reducing the formation of blood clots is essential to aging." Doctor Anthony Cichoke

"Nattokinase may reduce levels of compounds linked to blood clotting, and cut the risk of heart disease in people at-risk of the disease. In a study conducted in Taiwan, the enzyme was found to be able to reduce levels of blood clotting (coagulation) factors such as fibrinogen, factor VII and factor VIII in 45 men and women. These results, namely the observed reduction of the coagulation factors of fibrinogen, factor VII and factor VIII, suggest that nattokinase administration can be considered as a CVD nutraceutical. To our knowledge, this study is the first clinical trial reported in the literature to investigate the effects of nattokinase on the CVD-associated coagulation factors. Nattokinase supplementation can ameliorate blood viscosity and may reduce the incidence of CVD. In addition, both factors VII and VIII have been reported to have cross-sectional association with atherosclerosis and coronary heart disease and, prospectively, with coronary heart disease, stroke, ischemic heart disease and diabetes mellitus. The potent effects of nattokinase on lowering blood levels of factor VII and factor VIII may imply that it can be considered as a nutraceutical for several types of CVD."   Chien-Hsun Hsia et al, Nutrition Research.  

"Oxygen cannot stick to blood cells if the pH of the blood is acidic. And rather than do everything that they can to raise the pH back up to a normal pH of 7.4 so that the blood can function properly, they prefer surgery. All of the advice that they have stolen from naturopathic medicine about “deep breathing” will do them no good at all. You can breath pure oxygen until you catch on fire but if the blood pH is acidic, then the oxygen will not be able to be picked up by the blood cells. It is chemically impossible. The blood must be normal and normal blood has a pH of around 7.4 pH. Any vestigial traces of oxygen that the acid-drenched blood cells manage to pick up are stripped off early by the oxygen-starved cells along the way and never reach the deeper parts of the body where oxygen is most needed. And because the pH is acidic, carbon dioxide also is not transported efficiently and so builds up within the tissues leading both to cell death and to a cell-to-cancer de-evolution for survival.”  Curing Cancer with Baking Soda:

"There is one important thing they're not testing you for. And the latest research shows that this one thing is the most important CVD risk factor of all. It's blood viscosity."  Doctor Robert Rowen MD

"Not only has spirulina been shown to improve circulation and maintain healthy blood pressure, but Japanese scientists have discovered that it can also help detoxify the blood and maintain energy levels. Important to note in the area of prevention, spirulina is richly supplied with the blue pigment phycocyanin, a biliprotein which has been shown to support normal cell growth,"   Doctor Al Sears MD

"Lignans can help prevent tiny blood clots from forming in your blood, further reducing the risk of heart disease."   Lillian Thompson PhD Nutrition

"You can also see the effects of tissue acidity that leads to a cancerous state by viewing how the blood coagulates. If the blood is in a hypercoagulated state this indicates latent tissue acidosis and a marker for a cancerous or degenerative tissue state. This simple blood test can be done as an early warning to any cancerous state in any part of the body for the purposes of screening and prevention."    Doctor Robert Young MD

    

Wound Healing is Complex

"Normal hemostasis relies on the balance between procoagulant and anticoagulant activities. While platelets play a major role in procoagulant activities, vascular endothelial cells control the anticoagulant activities, notably by synthesizing vasorelaxing and platelet-inhibiting factors, such as NO and prostacyclin (Miller and Vanhoutte 1992 ). Recently we found that Welsh onion extracts modulate rat aortic vascular responses and in vitro human platelet function (Chen et al. 1999 ). Raw green extract caused vasorelaxation and antiplatelet effect by stimulating the release of endothelium-derived NO, which is a potent inhibitor of platelet aggregation and adhesion (Azuma et al. 1986 , Jen et al. 1995 , Radomski et al. 1987 ). On the other hand, the boiled extract stimulates the release of a constricting factor, most likely to be thromboxane A2, and potentiates platelet activity. Taken together with the current results, it is clear that the raw Welsh onion is antithrombotic."   Chronic Consumption of Raw Welsh Onion Juice Inhibits Rat Platelet Function, Note this is an excellent study delineating MANY health aspects

When you get cut you want a clot of form and the wound to heal. You do not want to bleed to death. OTOH you do not want clots to form inside your body for no good reason. In order to do this your body has evolved extremely complex systems. Over 40% of the 50,000 or so proteins in your body are involved in this complex process. Fibrinogen and plasminogen have been identified as key players in this game.

    

What is Hypercoagulated Blood?

                                                                                                                                                                     Normal Red blood Cells

 

                                                                                                                                 Red Blood Cells Aggregating

In the above picture we see the red blood cells aggregating or clumping up. In healthy blood not responding to the clotting process each cell is discrete and does not even touch its neighbor. This aggregation is the most visible manifestation of blood that will not flow as free as it should.

As we age the blood clotting mechanism tilts toward over clotting for many people. One result is what is called “Thick” or Hypercoagulated Blood. This can be a factor in MANY serious health problems including cardiovascular disease, cancer and other diseases. Doctor Gary Gordon believes "abnormal blood clots" are involved in 80% of all deaths. With hypercoagulated blood often the fibrin content of the blood builds up beyond homeostatic levels. Some of this excess fibrin may coat the blood vessel walls.

Hypercoagulated blood is also a mechanism by which a localized cancer often likely metastasizes. Medicine is in the process of accepting the need for long-term anti-platelet, anti-coagulant and anti-inflammatory therapy and addressing the vast panoply of problems with aging blood. IMO we can accomplish many of these goals by eating the right foods, supplementing and a few other simple actions. First we have to understand what is going on at least at the big picture level.

Your blood vessels are lined by special function cells called endothelial cells. These endothelial cells provide the interface between your flowing blood stream and the rest of your body; as such they perform many complex functions. The endothelial cells are designed to not clot inside the blood stream; when injured the clot will form within the artery wall and not within the blood stream. One of the endothelial functions is to help keep your blood from becoming hypercoagulated. It does this by releasing elements into the blood to thin the blood. If the endothelial cells become coated by fibrin your body's ability to dissolve the fibrin is lessened. Thus a vicious cycle is set up and may progress.

You can get a blood test (See Medical Testing Protocol) for viscosity and one for inflammation a C-reactive protein Blood Test (See CRP Blood Test Protocol). Do this next time you have a blood test, the few extra bucks will be worth it.

What is Disease? 

            
Negative Aspects of Hypercoagulated Blood

• Promotes thrombus, clot, formation

• Promotes cancer metastasis

• Promotes dementia

• Often Indicates Sugar Diabetes  

• Often Indicates bad cholesterol profile 

• Often indicates excess fibrinogen

• When fibrin coats the walls of the capillaries, nutrient and oxygen delivery to tissue is lessened

• Endothelial function is compromised resulting in numerous problems

• Two thirds of normal oxygen delivered to cells we know will cause cancer

• Low oxygen delivered to heart cells may impair heart function

• Can raise blood pressure

• The intestine may not be properly nourished resulting in digestive nutrient loss

• Many other negative aspects

    

Here is what I do to protect against Hypercoagulated Blood

(See Blood Coagulation Assess)

(See Blood Coagulation Detritus)

    

Risks for Cardiovascular Disease and blood viscosity

More

http://www.mnwelldir.org/docs/cardio/cardio3.htm

http://www.raysahelian.com/nattokinase.html

http://www.immunesupport.com/library/showarticle.cfm/ID/3110/e/1/T/CFIDS_FM/

http://www.gordonresearch.com/category_hypercoagulability.html