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Estrogen Protocol

"Estrogens are one of the two types of female sex hormones. They are secreted mainly by the ovaries and in smaller amounts by the adrenal glands and (in men) by the testes. Estradiol is the most potent of the estrogens. Functioning similarly to androgens, the estrogens promote the development of the primary and secondary female sex characteristics; they also stimulate linear growth and skeletal maturation. In other mammals these hormones have been shown to precipitate estrus (heat). The ovarian production of estrogen plummets during menopause."   Steroid Hormone

"You cannot make estrogen, testosterone, cortisone, and a host of other vital hormones without cholesterol.”      Doctor Don Rosedale, MD, widely considered to be the leading anti-aging doctor in the United States

“Melatonin blocks estrogen receptors on breast cells, stopping them from proliferating in response to estrogen and other factors that promote tumor growth. Melatonin also protects breast cells against chemical carcinogens, free radical damage, cortisol-induced damage, and non-estrogen dependent cellular changes that lead to breast cancer. Low dose melatonin therapy should be considered for any breast cancer patient on remission, and high dose for those with active disease.” Doctor Michael Lam MD

"Lignans may have powerful antioxidant properties that can help block the damaging effects of harmful oxygen molecules called free radicals. these free radicals are thought to cause changes in the body that can lead to cancer. Lignans subdue cancerous changes once they've occurred rendering them less likely to  race out of control and develop into full blown cancer."   Prevention, Flax seed provides 100s of times the phytoestrogen lignans as the next food source

"In recent studies scientists examined the effects of flax and sesame lignans on estrogen receptors in estrogen-positive breast cancers cells that had been implanted in mice. They found that flax lignans reduced proliferation and increased the rate of programmed cancer cell death of human breast cancer cells, while sesame lignans were much less effective."   Life Extension, Note sesame lignans ARE very effective in distributing vitamin E. 

"Researchers at the University of California, Los Angeles, have discovered that treatment with estrogen and progestin (the traditional synthetic prescription hormone replacement therapy, delivered in a combination of Premarin and Provera, also known as Prempro [Horse Urine] ) increases the number of deaths from lung cancer. The UCLA researchers’ finding, based on data from the Women’s Health Initiative, noted that women who used Prempro were 71 percent more likely to die from lung cancer. Other potential dangers associated with the use of Prempro include an increased risk of breast cancer and an increased risk of clots that can lead to a stroke."   Doctor Apar Ganti, University of Nebraska, The Lancet Sept 2009

“Researchers such as Dr. Abraham further postulate that Primary Postmenopausal osteoporosis is predominately a skeletal manifestation of chronic magnesium deficiency, facilitated by estrogen withdrawal during the postmenopausal period. ”  Doctor Michael Lam MD   Note also Vitamin C, Vitamin D and Vitamin K deficiency

"Remember, progesterone is the precursor, or basic raw material, for all the steroid hormones. So for many women who are really stressed and have been for years, they are relying in large measure upon alternative sources of adrenal hormones. With progesterone being the first of the volunteers to be changed into adrenal hormones, this leaves little or no progesterone left to perform its primary function, which was what? Right again, to maintain the dynamic balance with estrogen. The Doctor Within

“A large 7-year study included 240,073 pre- and post-menopausal women focuses on this. After adjusting for other risk factors, women who used estrogen for 6 to 8 years had a 40% higher risk of deadly ovarian tumors, while women who used estrogen drugs for 11 or more years had a startling 70% higher risk of dying from cancer of the ovaries.” Doctor Michael Lam MD Note this is a SYNTHETIC drug [Horse Urine] estrogen, the natural estrogen used in bio-identical treatment does not show this negative effect.

“Lignans may protect against cancer by favorably altering estrogen metabolism; inhibiting angiogenesis and inducing cancer cells to self destruct.”   International Journal of Cancer 2004, Flax seed provides 100s of times the phytoestrogen lignans as the next food source

“Maintaining hormonal balance is a key factor in preventing cancer and reversing hormone sensitive cancers. Cancers such as breast and prostate cancer are closely linked to estrogen dominance syndrome. Normalization of estrogen in our body can be achieved naturally with phyto-estrogen from food such as cruciferous vegetables, and supplements such as DIM. Natural progesterone cream that counterbalance the estrogen should also be considered. Melatonin is a natural hormone and a strong-antioxidant. Its use should be considered for many cancer patients, especially those with breast cancer.” Doctor Michael Lam MD   Note IMO most adults over 40 or so should be using melatonin for any sleep problems et al; find a reason your melatonin production is almost zero

"I have sympathy for the lay public who try to stay informed about life and dearth medical issues. With doctors making so many contradictory claims, it is no wonder that confused consumers die from lethal ignorance. The fact that  medical doctors continue to prescribe horse urine derived estrogens and synthetic progesterone with PROVEN risks is a testament to mainstream medicines apathy and ignorance. " William Faloon

“An estimated 1.2 million osteoporotic fractures occur annually and more than half occur in the vertebrae. The incidence of osteoporosis is directly correlated to testosterone production in men and estrogen and progesterone production in women.” Doctor Ross Hauser MD   Note balance those hormones!

“Hypothyroidism and/or iodine deficiency are associated with breast cancer. It is theorized that an absence of iodine renders the breast cells more sensitive to estrogen stimulation.” Murray & Pizzorno

“Taking synthetic estrogen cannot rebuild bones. It can temporarily slow the rate of bone loss, but when the HRT is stopped, osteoporosis soon catches up like the woman never took HRT at all. Is that temporary benefit worth a 9-14 times greater risk of cancer? Dr. Lee thinks not. (Lee, p152) In addition, many common drugs cause osteoporosis. Millions have been duped into the thyroid scam - told they were overweight because they were 'hypothyroid.' Synthroid to the rescue. What the doctor never tells you is that Synthroid stimulates osteoclasts to resorb bone. (Physicians Desk Reference) Remember how bone is built by living tissue? Well, that happens with the simultaneous action of two complementary types of blood cells: osteoclasts for tearing down old bone, and osteoblasts for building new bone. Obviously an imbalance in either one of these will cause a problem.” The Doctor Within

"Resveratrol is a phytoestrogen with demonstrated proapoptogenic effects that shows promise as an HRT alternative and chemoprotective agent for breast cancer."   Life Extension, Note well how about some resveratrol, grape seed extract and curcumin?

“There are safe, natural sources of estrogen which could be recommended in place of drugs. Many plants have safe, mild estrogen substances called phytoestrogens which are available to the body in minute, physiologic doses, and which can be used to safely supplement a declining estrogen output. Hormones are only needed and used by the body in tiny, very transient amounts. Transient means they only have to be around for a second or two. [sic.] A physiologic dose would mean a natural hormone like a phytoestrogen or a wild yam-derived progesterone in the same amount as what might be produced by the body for its own needs. Natural hormones can be swiftly broken down after they have performed their function. They don't just continue hour after hour like the synthetics or the xenoestrogens, which are given in sledgehammer amounts called pharmacologic doses. Big difference.” The Doctor Within, Note hormones are one of the smallest biologic units YOU DO NOT NEED LARGE AMOUNTS but hormones normally remain active for hours to a day or so

 “A curcumin-isoflavonoid combination suppressed the growth of estrogen receptor positive cancer cells up to 95%.” Verma et al 1998

“Normal estrogen stimulates breast and endometrial tissue. Excess estrogen causes excess stimulation of breast and endometrial collagen, resulting in fibroids in both locations. (McDougall, p 87) Another health detriment of estrogen is its destruction of B vitamins. Nutritionist Jean Sumption documents the opposition of estrogen with Vitamins B1, B2, B3, B5, B6 and other B-complex vitamins: Biotin, Choline, Folic Acid, PABA, and Inositol. Most functions of cell metabolism depend on B vitamins. Symptoms of depletion include fatigue, sluggish memory, hair loss, and aging.”       The Doctor Within

“Tocotrienols cause growth inhibition of breast cancer cells in culture independent of estrogen sensitivity and have great potential in prevention and treatment of breast cancer.”    Nesaretnam et al

"Post menopausal women placed on boron supplements had reduced calcium had magnesium loses and increased concentrations of circulation estrogen."   Sally Fallon

“Maintaining hormonal balance is a key factor in preventing cancer and reversing hormone sensitive cancers. Cancers such as breast and prostate cancer are closely linked to estrogen dominance syndrome. Normalization of estrogen in our body can be achieved naturally with phyto-estrogen from food such as cruciferous vegetables, and supplements such as DIM. Natural progesterone cream that counterbalance the estrogen should also be considered. Melatonin is a natural hormone and a strong-antioxidant. Its use should be considered for many cancer patients, especially those with breast cancer.” Doctor Michael Lam MD   Note IMO most adults over 40 or so should be using melatonin for any sleep problems et al; find a reason your melatonin production is almost zero

"Diindolylmethane (DIM) is found in vegetables like broccoli and cauliflower. It flushes excess estrogen out of your body, restoring your hormone levels back to normal. The more testosterone you have in relation to estrogen, the more potent – and virile—you’ll be. I recommend getting 100 mg of DIM a day."   Doctor Al Sears MD

“Sage has been used since ancient times to stop hot flashes. And it works.” Doctor Nan Fuchs PhD, Note this demonstrates sage's estrogenic effects  

“The blood level of cholesterol usually remains normal, (that is, below 200 units) except when total stress produces blocks to the usual metabolic pathways in which cholesterol is used to make various healthy homeostatic (balancing) hormones. In general, under stress, testosterone, estrogen, and even thyroid hormones decrease while cholesterol increases.” Doctor Norman Shealy MD

“Several studies have shown that pomegranate has antioxidant and anti-atherosclerotic properties attributed to the presence of multiple polyphenols such as tannins, flavonols, anthocyanins and ellagic acid ^{(1) (2)}. Pomegranate juice has been shown to suppress inflammatory cell signaling ⁽¹⁾, inhibit prostate tumor growth and lower serum PSA levels ^{(3) (4)}, and also inhibit aromatase activity, endogenous estrogen biosynthesis and breast cancer cell proliferation ⁽⁵⁾ in vitro. Consumption of pomegranate juice was found to benefit patients with carotid artery stenosis ⁽⁶⁾, in those with hypertension ⁽⁷⁾, and in patients with coronary heart disease (CHD)⁽⁸⁾.” Memorial Sloan-Kettering Cancer Center

“Doctor John Lee reported significant increase in bone density through natural progesterone. Natural progesterone is an antagonist of estrogen. While estrogen prevents the osteoclasts from breaking down bone, leading to increased bone density as the bone degradation process is slowed, natural progesterone actually increases the number of osteoblasts that are responsible for production of bone, leading to an increase in bone density.” Doctor Michael Lam MD

Women and Estrogen

Just reading the quotes above should make it clear how important the subject of estrogen is for women. Were I a woman I would become somewhat of an expert. Breast cancer alone requires this. The estrogen issue is not too complicated but it is BROAD and thus requires the integration of many of your health aspects. This is a GOOD thing, your health will benefit vastly IMO. Remember EVERYTHING is connected. Make those connections; use the salubrious NATURAL tools and REJECT the toxic drugs.

Women and Progesterone

When menopause starts, progesterone falls to almost zero. When I test women here in my clinic, their levels are often barely detectable. When I see these women during their first visit, they often tell me of weight gain, lack of sex drive, and poor sleep. Many are even on antidepressant drugs. When I see women with low progesterone, I prescribe a natural replacement. Within two weeks, they’re usually back to normal. A high-quality progesterone cream is often the best way to do it. The natural progesterone in the cream gets into your bloodstream and gently lifts your levels."   Doctor Al Sears MD

"With the cessation of 80% of hormonal production, a peri-menopausal woman suffers from estrogen, progesterone and testosterone deficiency. The replacement of estrogen alone does not correct an absent sex drive, loss of muscle tone and general lack of mental get-up-and-go." Doctor Edward Lichten, MD, PC, Note women must assure the testosterone and Pregnenolone feed stocks to assure good hormone production

Ladies reading the above quotes you can see how important progesterone is for you. Without enough progesterone  your estrogen is likely to be unbalanced. Please use NATURAL progesterone and estrogen should  you require hormonal supplementation. Horse Urine ugh!

Post and peri menopausal women often have too little estrogen as well as too little progesterone and too little testosterone. Some hormone production USUALLY shuts down around menopause; YOU need to do something NATURAL about it if you want to keep your womanly ways as well as your mind.

Men and Estrogen

"We tested estrogen blood levels in men based on published data indicating that when estrogen levels are unbalanced , the risk of degenerative disease in aging men skyrockets.37-40 Of concern to us 18 years ago were reports showing that excess estrogen contributes to the development of atherosclerosis.41,42 Human clinical studies conducted more than a decade later confirmed our suspicions. Men with even slightly elevated estrogen levels doubled their risk of stroke and had far higher incidences of coronary artery disease.43-45 ... The dramatic increase in mortality in men with unbalanced estrogen (estradiol levels either too high or too low) is nothing short of astounding. It uncovered a gaping hole in conventional medical practice that is easily correctable. "   Life Extension on Testosterone

"A study published in the Journal of the American Medical Association (JAMA) measured blood estradiol (a dominant estrogen) in 501 men with chronic heart failure. Compared to men in the balanced estrogen quintile, men in the lowest estradiol quintile were 317% more likely to die during a three-year follow-up, while men in the highest estradiol quintile were 133% more likely to die.56 The men in the balanced quintile-with the fewest deaths-had serum estradiol levels between 21.80 and 30.11 pg/mL. This is virtually the ideal range that Life Extension® has long recommended aging men strive for."    Life Extension on Testosterone

“A consistent finding in the scientific literature is that obese men have low testosterone and very high estrogen.” Life Extension, Note your "spare tire" converts testosterone to estrogen

"Diindolylmethane (DIM) is found in vegetables like broccoli and cauliflower. It flushes excess estrogen out of your body, restoring your hormone levels back to normal. The more testosterone you have in relation to estrogen, the more potent – and virile—you’ll be. I recommend getting 100 mg of DIM a day."   Doctor Al Sears MD

"Aging men are plagued with declining testosterone levels while their estrogen remains the same or even increases. This imbalance often sets the stage for a host of chronic inflammatory disorders while increasing the amount of abdominal adiposity." Life Extension

"The peel of lemons, limes, oranges and grapefruit contain the newly discovered nutrient flavones. Flavones have many  powerful health benefits such as lowering cholesterol, anti-cancer, anti-estrogenic, anti-CVD, anti-neurodegeneration, modulated cellular signaling and others."   Doctor Victor Marchione MD, Note find a way to eat these POWERFUL peels at least all the white and SOME of the outer rind. You can do it; it is a little work. I rarely waste this powerful food; I have gotten used to its taste

"To further substantiate the lethal impact of hormone deficiency, another study published in 2009 evaluated 3,014 men aged69-80 years. Serum levels of testosterone and estradiol were measured during a mean follow-up of 4.5 years. This study showed that men with low testosterone had 65% greater all-cause mortality, while men with low estradiol suffered 54% more deaths.69 Men low in estradiol and testosterone were almost twice as likely to die (a 96% increase in mortality) compared to men in the optimal ranges.69 This large study of aged men corroborates prior published reports linking imbalances of testosterone and/or estradiol with greater incidences of degenerative disease and death.10,12,38-40,46,70-76 "   Life Extension on Testosterone

"Men with even slightly elevated estrogen levels doubled their risk of stroke and had far higher incidences of coronary artery disease.43-45 Our early observations also revealed that men presenting with benign prostate enlargement or prostate cancer had higher blood estrogen levels (and often low testosterone).46-48 Subsequent clinical and laboratory studies helped confirm our early observations.49-53 Insufficient estrogen, on the other hand, predisposes men to ailments such as osteoporosis and bone fracture.54,55 The fact that 99% of men today have no idea what their blood estrogen levels are helps explain the epidemic of age-related disease that is bankrupting this nation’s medical system. "   Estrogen Balance Critical To Aging Men

“Our finding that estrogens have a fundamental role in the regulation of body fat and sexual function, coupled with evidence from prior studies of the crucial role of estrogen in bone metabolism, indicates that estrogen deficiency is largely responsible for some of the key consequences of male hypogonadism and suggest that measuring estradiol might be helpful in assessing the risk of sexual dysfunction, bone loss, or fat accumulation in men with hypogonadism.” 85"   Estrogen Balance Critical To Aging Men

"An acid found in pomegranates appears to block aromatase, an enzyme that converts androgen to estrogen, a hormone that plays a role in the development of breast cancer. Many women who have had breast cancer take medicines called aromatase inhibitors -- such as Pfizer's Aromasin, Novartis' Femara and AstraZeneca Plc's Arimidex -- to keep estrogen from stimulating tumors. Chen and colleagues studied whether compounds, or phytochemicals, in pomegranates can suppress aromatase and ultimately block cancer growth. They found that 10 natural compounds in the fruit may potentially prevent estrogen-related breast cancer. Shiuan Chen, of the City of Hope cancer research and treatment center in Duarte, California, believes the compounds would not be a replacement for aromatase inhibitors since they are not as potent as the real drugs. But, these compounds may be helpful for prevention rather than for treatment once the cancer has started."   Ray Sahelian

Both men and women can have unbalanced estrogen. Make sure yours is balanced. There are dozens of good natural methods to raise your testosterone. Please consider these BEFORE even considering a dangerous estrogen lowering drug. Often just raising your testosterone by good living will also raise or lower your estrogen as required.

You are also in BIG trouble if your estrogen is too LOW so make sure this is not the case.

DIM a special help for Estrogen - Progesterone Balance

DIM is a balancer of Estrogen metabolism and also raises progesterone level when necessary. Yes we men also have both of these hormones and they need to be balanced in both women and men. DIM has been proven to help the body to convert the most dangerous form of estrogen, estradiol into a less dangerous form estriol. This can trigger more testosterone to be released in your bloodstream.  Thus DIM contributes to lessening our ongoing problem with estrogen dominance (See Estrogen Dominance Protection Protocol).

Bioidentical Hormone Supplementation

"Bioidentical hormones have the same exact molecular structure as the hormones produced naturally within the body. The body does not distinguish between supplemental bioidentical hormones and the hormones produced within the body.4 As a result, bio-identical hormones are properly utilized, and are then able to be naturally metabolized and excreted from the body. The use of bioidentical HRT has increased during the last several years as women have sought out a more natural approach to restoring hormonal balance."    Bioidentical Hormones: Why Are They Still Controversial?

Ladies and gents if you need  hormones please GET HORMONES NOT DRUGS.

Important Estrogen Co-Factors and Issues   Please read the above quotes until  you become well acquainted with the large net of estrogen related issues and tools

• B Vitamins

• Balance between Estrogen/Testosterone

• Bone Health

• Boron

• Cancer Prevention

• Cholesterol

• Citrus Peels

• Curcumin

• DIM  and cruciferous vegetables

• Estrogen Drugs vs safe, natural sources of estrogen

• Flax

• Hormone sensitive cancers

• Horse Urine derived Estrogen

• HRT vs safe, natural sources of estrogen

• Iodine

• Lignans

• Low Estrogen/Testosterone

• High Estrogen/Testosterone

• Maca

• Melatonin

• Normalization of estrogen

• Pomegranate

• Progesterone

• Phytoestrogens

• Resveratrol

• Sage

• Stress

• Testosterone

• Tocotrienols

• Turmeric

Caution: Do not take this or any other hormone directly without researching hormone supplementation and having your levels checked. In particular do not DIRECTLY take supplemental hormones if under the age of about forty. It is strongly suggested you consult with a knowledgeable Integrative Doctor on hormone supplementation and only take bio-identical hormones. 

Ladies you MUST explore bioidentical hormones if you require direct hormone supplementation. The drug forms of estrogen and progesterone are BAD NEWS and have PROVEN this for many decades. Natural Bioidentical hormones are in the bio identical form as your natural hormones and are given in identical amounts as your body requires.

Men should also use a NATURAL hormone form if they require a direct supplemental hormone.

Also See Progesterone

Also See PMS

Also See Estrogen dominance

Also See Hormones

Also See Phytoestrogen

Also See DIM

This File was last updated on 05 February 2020 01:48 PM

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