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AMPK Protocol

     

If you are over 50 or so, it’s critical that you understand AMPK

"The notion that we “die of old age” is a common and misleading myth of modern medicine."   AMPK and Aging

       

"If you’d like to meaningfully extend your healthy life span, activating your cellular AMPK is critical. This is important because in response to aging, excess calorie consumption, and/or low levels of physical activity, AMPK activity markedly declines."   Life Extension   Note this implies that you can do a LOT just by staying in shape as you grow older

    

"To really understand aging, we have to recognize that it is not an automatic result of time passing, but rather the result of reversible events that occur in all cells, regardless of the tissue or organ system to which they belong. One of the most fundamental of those events is a decline in activity of AMPK, the universal cellular energy sensor that dictates whether cells store energy as dangerous fats or use energy efficiently to power vital processes. Activated AMPK creates a more youthful energy profile, one with only small amounts of fat stores, a great deal of energy for useful activity, and rapid recycling of old, damaged proteins. ... It’s critical that you understand AMPK and how to optimize its activation in your body if you want to extend your life span in the best possible state of health."   AMPK and Aging

"No matter which organ system or underlying disease is involved, if you trace the pathological process far enough back, you will likely encounter a problem related to insufficient AMPK activity. This is good news for people who believe in significantly extending their life spans. That’s because a growing body of evidence suggests that boosting AMPK activity can prevent, and even reverse,1-4 life-shortening effects of aging. This includes disorders as disparate as cardiovascular disease, diabetes, liver and kidney failure, neurodegenerative diseases (e.g., Alzheimer’s), cancers, and more.5 In fact, scientists are beginning to refer to AMPK as literally a suppressor of aging itself.6 Substantial evidence indicates that restoring AMPK activity not only increases longevity, but works to fight the symptoms of aging in individual body systems."    AMPK and Aging

"AMPK has been referred to as a “metabolic master switch.”14 AMPK controls a gamut of metabolic pathways that enable us to extract energy from food, store and distribute that energy safely through the body, and ultimately use that energy for everything from moving and mating to talking and thinking, and even to understanding these very words as you read them.14,15  ... And that is precisely where AMPK comes into play. AMPK is biochemically activated in the presence of rising levels of AMP (and decreasing levels of ATP).5 Activated AMPK, in turn, increases fatty acid oxidation and glucose transport, thereby releasing additional energy from available or stored sources (fats and sugars)."   AMPK and Aging

"The modern picture of the overweight American, living a sedentary lifestyle and enjoying an overabundance of carbohydrates and calories, is harmful for AMPK activation and therefore deadly. We are literally eating ourselves to death. By suppressing AMPK activation, we develop dangerous fat deposits, especially in the belly region. Burgeoning fat masses reduce insulin sensitivity37-39 and produce system wide inflammation,40 which may contribute to “metabolic syndrome."   AMPK and Aging

If you are over 50 or so, it’s critical that you understand AMPK.

AMPK is an enzyme your body produces that enhances the energy production of every cell in your body. The aging of cells is the chief factor causing you to age. Just living right will allow your body to produce good AMPK up to the age of 60 or so, after that some supplement help can't hurt. 

    

Activated AMPK Benefits

"The good news, as we’ll now see, is that we can restore our dwindling AMPK activity through a combination of lifestyle, diet, and supplement interventions,"   AMPK and Aging

  • Promotes Robust Good Health while you are alive

  • Promotes Longevity

  • Targets damaging factors of aging

  • Promotes Cardio Vascular Health

  • Promotes mitochondrial production

  • Promotes Immune Function

  • Promotes Liver Health

  • Optimizes cellular energy production

  • Anti-Cancer

  • Anti-Diabetes

  • Anti-Metabolic Syndrome

  • Suppresses Fat Storage

     

Avoid For Activated AMPK

Lifestyle And Genetic Factors Impair AMPK Activation

Image Article

    

Promoting AMPK Activation Naturally

"The good news, as we’ll now see, is that we can restore our dwindling AMPK activity through a combination of lifestyle, diet, and supplement interventions, with the possibility of significantly increasing life span through mitigation of potentially fatal symptoms of aging. The most compelling evidence that activating AMPK can help you live longer comes from a study just released in 2014, in which diabetic patients treated with the drug metformin, a potent AMPK activator, lived a median of 15% longer than did matched controls without diabetes."   AMPK and Aging

"It is evident that you should do all you can to maintain and even boost your AMPK activity if you want to slow aging throughout your body. You can use drugs, but obtaining prescriptions for drugs like metformin is challenging unless you happen to be a type II diabetic. More natural ways to boost AMPK involve lifestyle changes. Regular moderate exercise is a good approach, since we know that muscle contractions are potent triggers for AMPK activation.9,14,21 And of course, an exercising body uses up ATP, generating higher AMP levels, activating AMPK.5 As we age past 60, however, the ability of vigorous exercise to increase AMPK diminishes."   AMPK and Aging

"But, regardless of which of these strategies you try, or even if you haven’t the discipline to do any of them, there is still plenty you can do to boost your AMPK activity by using certain supplements. Indeed, many supplements originally recognized for their nutritional properties are now being found to increase AMPK activation, which may contribute to their life-extending effects.102 "   AMPK and Aging

"Gynostemma Pentaphyllum is a plant which is sometimes referred to as either 'Southern Ginseng' or 'Cheap Ginseng' as it was used as a cheap substitute for Panax ginseng (as aside from Codonopsis pilosula, which was used as an adulterant for Panax Ginseng to sell it at the normal price but cut costs). Surprisingly, Gynostemma has a good content of Ginsenosides that were once thought to be wholly unique to Panax Ginseng. As such, the biological effects of Gynostemma and Panax seem to be quite similar except Gynostemma may be more anti-diabetic (due to the unique Gypenosides in Gynostemma, that are not in Panax)."   Gynostemma Pentaphyllum

"Most of its 'beneficial' effects beyond the diabetic effects (which are mediated by a possible mix of AMPK activation and PTP1B inhibition; the amount each contributes to the overall effects unknown) come from inducing antioxidant enzymes and protecting cells from oxidative damage over time. There seems to be a motif where preloading and chronic loading is very protective at low doses, and acute supplementation or rehabilitation (taking the supplement after the stressor) appears to be less effective. As such, the health effects of Gynostemma Pentaphyllum appear to be more prophylactic rather than rehabilitative or therapeutic. This herb is also touted for youthfulness and longevity, but neither claim has been explored."   Gynostemma Pentaphyllum

"If you’d like to meaningfully extend your healthy life span, activating your cellular AMPK is critical. This is important because in response to aging, excess calorie consumption, and/or low levels of physical activity, AMPK activity markedly declines."   Life Extension   Note this implies that you can do a LOT just by staying in shape

 

     

Life Extension has an AMPK Activating Supplement

"AMPK Activator is an oral formula that turns on AMPK (adenosine monophosphate-activated protein kinase), an enzyme that serves as the body’s master regulating switch. Increased AMPK activity helps to revitalize aging cells, promote mitochondrial production, and inhibit multiple damaging factors associated with aging. But despite all of the scientific research, supplemental support for youthful AMPK levels has been largely non-existent … until now. The clinically validated combination of ActivAMP® (Gynostemma pentaphyllum) and rose hip plant extracts, provides nutrient support for youthful AMPK levels."    Life Extension has an AMPK Activating Supplement

If you are over 50 or so, feeling too old and have the bucks you may want to try it. First do all  the good living things to produce your own AMPK IMO.

    

Also See Arteriosclerosis Protocol   Also Cuts Life Short By SLOWING down cell activity by a NON-Energy means

 

This site was last updated on: 14 June 2016 08:14 AM

The information provided throughout this site should not be used during any medical emergency or for the diagnosis or treatment of any illness. Call 911 for all medical emergencies. A licensed integrative physician should be consulted for diagnosis and treatment of any and all illnesses you can not handle yourself. You and your doctor should reach an informed consensus on diagnosis and treatment. It is incumbent on YOU to know enough about your illness to do this. Blindly following  some doctors orders will in the end sink you IMO. Links to other sites are provided for the targeted information indicated and links should not be regarded as an endorsement of all additional information that those other sites may provide although these sites are in general very good to excellent or I would not use them. Trust but verify. Trust government at your own risk. IMO toxic depopulation  politics is the cause of MOST of our health and MANY of our death problems. Trust yourself because YOU have become knowledgeable enough to trust.  YOU are the ONLY one responsible for your life and health; others may be indirectly responsible for your death; once you realize this your life will get MUCH better and also in ways other than your health.