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Natural Killer Cells Protocol

"The first line of defense against new invaders is our natural killer (NK) cells. NK cells come fully equipped to recognize any cells that don’t belong in your body.65 Such cells include those whose replicative machinery has been taken over by a virus, and also cells that have gone rogue to replicate without natural controls, such as cancer cells.16. As we age, NK cells lose their functionality, thus leaving us far more vulnerable to viral diseases—and the formation of tumors.9,10 Aging humans don’t have to succumb to this massive loss of NK cell function. Scientists have uncovered an enzymatically modified rice bran that has been shown to increase NK cell activity in circulating blood cells by up to 84%!11"   Activate Your Natural Killer Cells

"Natural killer cells (NK cells) are one of your body’s most powerful defenses against infections and cancer.13-15 These tiny security guards seek and destroy cells that have been transformed by an infection with a virus or by one of many malignant changes that transform them into cancer cells.9,16 NK cells work by triggering apoptosis (programmed cell death) in cells that have been transformed by a virus or malignancy.17,18 Without this critical defense mechanism, viruses can be spread throughout the body and cancer cells can form invading, metastasized tumors.9,19 The health of these cells is critical to a robust immune system. Unfortunately, your NK cell function rapidly declines as part of the natural decline in your immune system as you age.20-22 This degeneration of immune function is medically termed immune senescence."   Activate Your Natural Killer Cells

"A review article entitled Opioid Therapy for Chronic Pain, published in a 2003 issue of the New England Journal of Medicine, states: Opioid-Induced Immune Modulation: .... Preclinical evidence indicates overwhelmingly that opioids alter the development, differentiation, and function of immune cells, and that both innate and adaptive systems are affected. Bone marrow progenitor cells, macrophages, natural killer cells, immature thymocytes and T cells, and B cells are all involved. The relatively recent identification of opioid-related receptors on immune cells makes it even more likely that opioids have direct effects on the immune system." Doctor Joseph Mercola, Note here is another reason to exercise which produces the natural opioids we know as endorphins

“Supplementing with selenium, 200mcg/day in individuals with normal blood levels of selenium resulted in a 118% increase in the ability of lymphocytes to kill tumor cells and an 82% increase in the activity of natural killer cells.” Roy, Note "normal" is often suboptimal due to the poor health status of the "normal" person

“The study showed that severe vitamin E deficiency causes impaired NK cell activity but that the condition is reversible with alpha-tocopherol supplementation.”  Adachi et al, Note NK, natural killer, cells are a main component of your passive immune system

"Studies suggest that Siberian Ginseng may help reduce blood sugar levels, balance blood pressure levels, and enhance the immune system by boosting the body's production of natural killer cells."  Siberian Ginseng

“The study showed that severe vitamin E deficiency causes impaired Natural Killer cell activity but that the condition is reversible with alpha-tocopherol supplementation.”  Adachi et al

“Oral L-Glutamine in rats upregulated tissue glutathione, increased natural killer cell activity and tumors were inhibited.”  Klimberg et al

“If your body has inadequate zinc stores, you will experience increased susceptibility to a variety of infectious agentsYour white blood cells simply can't function without zinc. Zinc affects multiple aspects of your immune system, including neutrophils, natural killer cells, phagocytosis, cytokine production, antibody production, and even gene regulation within your lymphocytes. Zinc is involved in many basic cellular functions including DNA replication, RNA transcription, cell division and activation, and stabilization of cell membranes.”   Zinc is a Key Mineral for Your Immune Health

"Beta-1,3 glucan has incredible immune building power. And mushrooms are one of the richest sources on earth! Medicinal mushrooms are proven in numerous medical studies to increase the number and activity of Natural Killer (NK) cells in your body.”   Doctor Nan Fuchs PhD

"A unique product, enzymatically modified rice bran (EMRB), has now been developed, EMRB boosts NK cell activity by nearly 84%. EMRB is also effective at reducing deaths from certain cancers, further testimony to its boost of NK function.  ... An especially promising early animal study demonstrated the power of EMRB for boosting NK cell activity. When old mice with age-related reduction of NK function were injected with EMRB, they showed a greater than five-fold increase in NK cell activity within just two days of treatment.46 The enhanced NK activity in this study also resulted in increased binding of NK cells to target tissues and boosted the amounts of cell-killing chemicals inside each cell. The wintertime viral season is precisely the time that this product should be used for optimum protection. ,,, Once the flu season is over, you can stop the EMRB supplement until next year’s season begins. All-year immune support can be obtained by supplementing with other immune enhancers such as Cistanche and Reishi that provide broad-spectrum immune support, including enhanced NK cell activity. "    Activate Your Natural Killer Cells

"The first line of defense against virus-infected28-31 and cancer cells is our natural killer cells.32-45 Young individuals have high levels of functional natural killer (NK) immune cells, but this declines with aging. 46-49 In elderly subjects, decreased NK cell activity is associated with an increased incidence and severity of viral infections such as shingles, influenza, and cytomegalovirus (CMV). 47,50-53 Natural killer cells originate in the bone marrow (like other immune cells) and go through a maturation process that enables them to participate in early control of microbial infections and cancers.47,62 "   How Immune Decline Hastens Aging

Your innate immune system's Natural Killer Cells provide invader killing power for your immune system. It is not too hard to think of these IMPORTANT parts of your immune system when supplementing.  Vitamin D and vitamin C are required in good amounts for a strong NK response.

The lack of vitamin D and to some degree vitamin C, accounts for much of our susceptibility to contacting the seasonal flu all other viral, bacterial and infective diseases. Since our population is severely deficient in Vitamin D and Vitamin C IMO use to onset of flu season, September, as a reminder to get  your vitamin D and C UP. The worthless and dangerous "flu shot" cannot help but the anti-infective Vitamins especially Vitamin D will prevent all serious flu and other viral infections.

Several vitamins and supplements are NK response enhancing and IMO you should assure they aid your NK response.

If you use EMRB (IP6) an inexpensive very salubrious supplement during the flu season you will be doing your innate immune system a favor.

 

Vitamin D and Natural Killer Cells

The simple primal act of getting noontime sun on your bare “unprotected” skin in large amounts just may be the most important single thing you can do for your health. 

The simple primal act of getting LOTS of the high noon sun on your bare “unprotected” skin in large amounts just may be the most important single thing you can do for your health. If the sun casts a shadow longer than you are tall you cannot make adequate vitamin D from the sun. You MUST take vitamin D3 at the daily rate of about 1000 IU/20 pounds of body weight.  Vitamin D Expert Doctor Holick’s Excellent Entertaining Amusing Video Vitamin D Presentation

IMO get an hour or more of noontime sun/day in season or 1000 IU of vitamin D3/20 pounds body weight/day

Don’t be afraid of Sunshine, Vitamin A, Vitamin C, Vitamin D or Cholesterol; learn their properties and safely and freely use these powerful health tools

"It is high time that worldwide vitamin D nutritional policy, now at a crossroads, reflects current scientific knowledge about the vitamin's many benefits and develops a sound vision for the future.”   Doctors Norman and Bouillon 

"Cedric Garland, DrPH, and colleagues selected 32 studies that provided data on a total of 566,583 men and women for their analysis. They determined that having a vitamin D level of 30 ng/mL is associated with approximately half the risk of dying over an average nine years of follow-up in comparison with lower levels. Dr. Garland, who is a professor at UC San Diego, noted that serum levels of vitamin D lower than 30 ng/mL are estimated to exist in two-thirds of the US population. Life Extension continues to recommend that people maintain 25-hydroxyvitamin D blood levels between 50-80 ng/mL."   Review Affirms Higher Vitamin D Levels Are Associated With A Reduced Risk Of Premature Mortality

"Without sufficient amounts of vitamin D the cell cannot access it's DNA library and its functions are thereby impaired. The cell needs vitamin D to make the tools that are needed for everyday activity. This is why vitamin D can function in so many tissues and affects so many different diseases and health conditions."  Doctor Robert Heaney Vitamin D Researcher

"If you want to maintain a level of 32 ng/ml you need to ingest 4,000 IU of vitamin D3/day. IMO the upper safe dose is 10,000 IU a day. If you have a serious health problem these large doses are not going to hurt."   Doctor Robert Heaney Vitamin D Researcher

    

The lack of vitamin D and to some degree vitamin C, accounts for much of our susceptibility to contacting the seasonal flu all other viral, bacterial and infective diseases. Since our population is severely deficient in Vitamin D and Vitamin C IMO use to onset of flu season, September, as a reminder to get  your vitamin D and C UP. The worthless and dangerous "flu shot" cannot help but the anti-infective Vitamins especially Vitamin D will prevent all serious flu and other viral infections.

Dozens of our body’s systems depend on vitamin D. Low levels of vitamin D contributes, is often a MAIN factor, in hundreds of diseases. Many diseases are more prevalent the farther north or south you get from the equator.  For example without vitamin D you cannot build bone no matter how many calcium pills you pop or how much milk you drink. Sure enough osteoporosis is more prevalent the farther north or south you get from the equator. Vitamin D boosts your production of cathelicidin which your natural killer cells use to destroy microbes. Without vitamin D your immune system will operate on a much lower response level allowing disease to get a foothold in your body. Doctor Heaney explains why this is so. 

As doctor Heaney says you need about 32 ng/ml just to access your genome. The vitamin D must be operating to correctly create your epigenome. About 85% of us have less than this. IMO this may account for MANY of the "health problems" we are experiencing in today's world of artificial food and deceitful, treasonous, senseless, pernicious noon sun avoidance. What they have given us with this sun avoidance crap is the inability to correctly read our genome. Thanks CDC!

    

Aging and Natural Killer Cells

"Healthy NK function is critical in eliminating transformed cancer cells.27,44,63 NK cells are also involved in the elimination of senescent cells62,64 that otherwise cause chronic inflammation.27,65-67 The age-related decrease in functional NK cells is likely to have wider implications for the health of older adults than currently understood by the mainstream. If an aging person is to better manage debilitating and deadly infections and malignancies, maintaining youthful NK function is critical."    How Immune Decline Hastens Aging

"Evidence has emerged that has shown that in addition to eliminating transformed cells, NK cells are involved in many other biological processes such as immune regulation, antimicrobial immune responses, and the recognition and elimination of senescent cells… Thus, the decrease in NK cell function that accompanies physiological aging is likely to have wider implications for the health of older adults than originally thought.”   Aging Research Reviews-May 6, 2013. “The Impact of Aging on Natural Killer Cell Function and Potential Consequences for Health in Older Adults.”

"When you were younger, your NK cells, which are part of your innate immune system, could destroy the new strain of virus while your adaptive immune system “learned” its properties and then made antibodies to destroy any remaining virus.30-33 But because your NK cell function declines with age, you can easily be rapidly overwhelmed by new viral strains before your slower adaptive immunity can develop. Similarly, older adults are at an increased risk of cancer because falling NK function fails to destroy malignant cells early on, allowing them time to develop various tricks that evade adaptive immunity while they grow into life-threatening tumors. Younger people have more robust NK function, which helps explain why cancers are generally so rare before late middle age. "   Activate Your Natural Killer Cells

"Shingles occurs when our immunity to dormant chickenpox viral infection declines. It manifests as an extremely painful skin lesion that can last for months. 54 Influenza, commonly called the flu, is a virus that inflicts its lethal effects mostly on the elderly, who represent the largest portion of the population that suffers immune dysfunction.1,7 Cytomegalovirus (CMV) is a chronic infection that, as you’ll discover later in this issue, may contribute significantly to degenerative disease. About 90% of older people showed history of CMV infection on lab testing compared to about 60% of the general population. 55 Increased prevalence of CMV in the elderly is thought to lead to decreased immune surveillance.56-61 "   How Immune Decline Hastens Aging

"Overlooked are studies showing vibrant NK function is crucial for the immune system to recognize and eliminate unhealthy/infected cells and dysfunctional (senile) cells.27,115 A pathologic consequence of too many senile cells is tissue/organ damage and chronic inflammation.116-119 Senile (senescent) cells reside in a state of irreversible cellular paralysis. Your body wants them to die and disappear, but they linger on for dangerously long periods. While these senile cells contribute nothing to healthy function, they remain metabolically active, secreting an array of dangerous growth factors and pro-inflammatory cytokines. Functional NK cells can eliminate senile cells before they buildup to lethal levels. When NK cells are hampered by aging, however, they are less able to remove deadly senile cells from our bodies. "   How Immune Decline Hastens Aging   Note this function of NK cells is VERY important for us old fogies.

As we grow older our NK cell response can grow weaker and needs some looking after. If we fail to do this we will come down with "everything that is going around". This is no way to live and you need not do it. I have used IP6 for many years mostly as a phytic acid cleanse and HDL booster and am now using it in addition as a NK cell booster. I take plenty of EMRB.

      

Natural Killer Cell Enhancing

"Mainstream medicine has little to offer to counteract declining NK cell function. ... A better approach would be to change the way the body responds to threats like viruses and tumor cells by directly boosting NK cell function and restoring waning immunity caused by immune senescence.5,43 "   Activate Your Natural Killer Cells

"Cistanche plant extract stimulates development of naïve T cells and leads to a lower number of memory T cells, which creates a more balanced and healthier immune response. Cistanche also increases natural killer (NK)-cell activity (cells that seek and destroy cells infected with viruses or transformed by cancer)—an action that has been shown in animal research to result in lifespan increase. A human study found that individuals taking standardized Cistanche had impressive improvements in their immune profiles after 12 weeks. This included an 11.7% increase in natural killer cell activity and a 20.2% increase in the ratio of CD4 to CD8 cells, which is an indicator of healthier, more youthful immune function."   Winterize Your Immune Defenses

"Aging individuals are more vulnerable to viral (and other) diseases, in part because aging diminishes the functionality of natural killer (NK) cells. Scientists have uncovered an enzymatically modified rice bran that has been shown to increase NK-cell activity by up to 84%. Enzymatically modified rice bran is produced by exposing crude fiber from rice bran to enzymes isolated from the Japanese culinary mushroom shiitake (Lentinula edodes). In a four-month study conducted on individuals who were initially low in NK-cell activity, supplementation with one gram (1,000 mg) of enzymatically modified rice bran per day led to a four-fold increase in NK-cell activity at two months, compared to control responses. And at the end of four months, participants showed a seven-fold increase in NK cell activity. Consider adding 500 mg to 1000 mg daily during the wintertime virus season for added protection."   Winterize Your Immune Defenses

 

 

 

 

 

 

 

 

 

This site was last updated on: 10 February 2017 09:32 AM

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